White to slightly yellowish free-flowing powder; Soluble in water and other common solvents; Hygroscopic; Film-forming.
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| Test Items | Specifications |
|---|---|
| Appearance | White to Creamy white,free-flowing powder |
| K value | 27.0-33.0 |
| Aldehydes | ≤500 ppm |
| Peroxides | ≤400 ppm |
| Hydrazine | ≤1 ppm |
| 2-pyrrolidone | ≤0.5 % |
| N-vinylpyrrolidone | ≤10 ppm |
| VAc | ≤10 ppm |
| Heavy metals | ≤10 ppm |
| Loss on drying | ≤5.0% |
| Sulfatedash | ≤0.1% |
| Vinyl acetate | 35.3-42.0% |
| Nitrogen | 7.0-8.0% |
PVP VA64 possesses excellent adhesion and film-forming properties for broad application in the pharmaceutical field:
Suitable for wet or dry granulation and direct compression processes, improves particle compressibility;
Permeable film coating for tablet and sugar coatings to protect against splitting, decrease moisture sensitivity and provide good film adhesiveness, elasticity, and hardness;
For use in taste-masking and component of the matrix material used in controlled-release formulation;
For solid dispersion processes to enhancing bioavailability and improve drug solubility.
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