Crospovidone-HENAN PENGFEI NEW MATERIALS

Crospovidone

Pharmacopoeia NameCrospovidone (Crospovidonum)
Chemical DescriptionCroslinked PVP, Crospovidone,Insoluble PVP, Polyvinylpolypyrrolidone
INCI/CTFAInsoluble PVP
Molecular Formula(C₆H₉NO)n
CAS No9003-39-8 / 25249-54-1
MOQ100KGS
PropertiesCrospovidone is hygroscopic, insoluble in water and all other common solvents, but it swells rapidly in aqueous solution without any gel formation. It's classified as Crospovidone Type A and Type B according to the different particle size.

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Product Parameters

Product	Crospovidone Type A	Crospovidone Type B
Appearance	White or yellowish-white powder
Identification	Meet ID Tests
Solubility	Practically insoluble in water, in alcohol and in methylene chloride
Water-soluble substances	1.0% Max	1.0% Max
pH (1% in water)	5.0 - 8.0	5.0 - 8.0
Loss on Drying	5.0%Max	5.0%Max
SulphatedAsh	0.1%Max	0.1%Max
Nitrogen content	11.0-12.8%	11.0-12.8%
Impurity A	10ppm Max	10ppm Max
Peroxide(As H₂O₂)	400ppm Max	400ppm Max
Heavy Metal	10ppm Max	10ppm Max
Particle Size (μm), ≥80%	50-300	5-50

Application Area

In the pharmaceutical industry, Crospovidone are widely used as:

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